GABA A Receptor alpha 5 antibody [N2C2], Internal
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||52 kDa (note)
|Positive Controls||NT2D1 , PC-3 , U87-MG , SK-N-SH , Neuro2A|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||gamma-aminobutyric acid (GABA) A receptor, alpha 5|
|Product Description||Rabbit Polyclonal antibody to GABA A Receptor alpha 5 (gamma-aminobutyric acid (GABA) A receptor, alpha 5)|
|Background||GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq]|
|Synonyms||MGC138184 antibody, GABRA5 antibody, GABA(A) receptor subunit alpha-5 antibody, gamma-aminobutyric acid receptor subunit alpha-5 antibody, "gamma-aminobutyric acid (GABA) A receptor, alpha 5 antibody"|
|Cellular Localization||Cell junction , synapse , postsynaptic cell membrane; Multi-pass membrane protein , Cell membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GABA A Receptor alpha 5. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (100%), Bovine (98%)|