|Full Name||galactosamine (N-acetyl)-6-sulfate sulfatase|
|Product Description||Rabbit Polyclonal antibody to GALNS (galactosamine (N-acetyl)-6-sulfate sulfatase)|
|Background||This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq]|
|Synonyms||FLJ17434 antibody, FLJ42844 antibody, FLJ98217 antibody, GALNAC6S antibody, GAS antibody, MPS4A antibody, GALNS antibody, galactose-6-sulfate sulfatase antibody, chondroitinase antibody, N-acetylgalactosamine-6-sulfate sulfatase antibody, galNAc6S sulfatase antibody, chondroitinsulfatase antibody, N-acetylgalactosamine-6-sulfatase antibody, galactosamine (N-acetyl)-6-sulfate sulfatase antibody|
|Cellular Localization||Lysosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GALNS. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Xenopus Tropicalis, Dog, Pig, Bovine|
|Predict Reactivity Note||Zebrafish (81%), Xenopus laevis (84%), Xenopus Tropicalis (80%), Dog (92%), Pig (91%), Bovine (91%)|