|Full Name||glycine amidinotransferase (L-arginine:glycine amidinotransferase)|
|Product Description||Rabbit Polyclonal antibody to GATM (glycine amidinotransferase (L-arginine:glycine amidinotransferase))|
|Background||This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq]|
|Synonyms||AGAT antibody, AT antibody, GATM antibody, transamidinase antibody, L-arginine:glycine amidinotransferase antibody, "glycine amidinotransferase, mitochondrial antibody", glycine amidinotransferase (L-arginine:glycine amidinotransferase) antibody|
|Cellular Localization||Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side (Potential) , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GATM. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Dog, Pig, Chicken, Bovine|
|Predict Reactivity Note||Rat (97%), Zebrafish (87%), Xenopus laevis (91%), Dog (95%), Pig (94%), Chicken (91%), Bovine (94%)|