GCLM antibody [N1N3]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||31 kDa (note)
|Positive Controls||HeLa , 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||glutamate-cysteine ligase, modifier subunit|
|Product Description||Rabbit Polyclonal antibody to GCLM (glutamate-cysteine ligase, modifier subunit)|
|Background||Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq]|
|Synonyms||GLCLR antibody, GCLM antibody, GSC light chain antibody, gamma-ECS regulatory subunit antibody, GCS light chain antibody, "glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD) antibody", glutamate--cysteine ligase modifier subunit antibody, glutamate--cysteine ligase regulatory subunit antibody, gamma-glutamylcysteine synthetase regulatory subunit antibody, glutamate-cysteine ligase regulatory protein antibody, "glutamate-cysteine ligase, modifier subunit antibody"|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human GCLM. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Bovine (100%)|