|Full Name||guanylate cyclase 1, soluble, alpha 3|
|Product Description||Rabbit polyclonal antibody to GCS-alpha-3 (guanylate cyclase 1, soluble, alpha 3)|
|Background||Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM]|
|Synonyms||GC-SA3 antibody, GUC1A3 antibody, GUCA3 antibody, GUCSA3 antibody, GUCY1A1 antibody, GUCY1A3 antibody, guanylate cyclase soluble subunit alpha-3 antibody, GC-S-alpha-1 antibody, soluble guanylate cyclase large subunit antibody, GCS-alpha-1 antibody, GCS-alpha-3 antibody, "guanylate cyclase 1, soluble, alpha 3 antibody"|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human GCS-alpha-3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Japanese medaka, Dog, Pig, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (97%), Zebrafish (83%), Japanese medaka (80%), Dog (98%), Pig (97%), Bovine (96%)|