GDF5 antibody [C3], C-term
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||55 kDa (note)
|Positive Controls||293T , A431 , H1299 , NIH-3T3 , JC|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||growth differentiation factor 5|
|Product Description||Rabbit Polyclonal antibody to GDF5 (growth differentiation factor 5)|
|Background||The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. [provided by RefSeq]|
|Synonyms||BMP14 antibody, CDMP1 antibody, LAP4 antibody, OS5 antibody, SYNS2 antibody, GDF5 antibody, cartilage-derived morphogenetic protein 1 antibody, growth/differentiation factor 5 antibody, GDF-5 antibody, cartilage-derived morphogenetic protein-1 antibody, radotermin antibody, CDMP-1 antibody, growth differentiation factor 5 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GDF5. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Pig, Rabbit, Chicken, Bovine|
|Predict Reactivity Note||Xenopus laevis (100%), Pig (100%), Rabbit (100%), Chicken (100%), Bovine (100%)|