GFM2 antibody [N3C2], Internal
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||87 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , Neuro 2A , C8D30|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||G elongation factor, mitochondrial 2|
|Product Description||Rabbit Polyclonal antibody to GFM2 (G elongation factor, mitochondrial 2)|
|Background||Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms. [provided by RefSeq]|
|Synonyms||EF-G2mt antibody, EFG2 antibody, MRRF2 antibody, MST027 antibody, RRF2 antibody, RRF2mt antibody, hEFG2 antibody, mEF-G 2 antibody, GFM2 antibody, "elongation factor G 2, mitochondrial antibody", "ribosome-releasing factor 2, mitochondrial antibody", MSTP027 antibody, mitochondrial elongation factor G2 antibody, mitochondrial ribosome recycling factor 2 antibody, "G elongation factor, mitochondrial 2 antibody"|
|Cellular Localization||Mitochondrion |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GFM2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (87%), Rhesus Monkey (98%), Bovine (91%)|