|Full Name||gamma-glutamyl carboxylase|
|Product Description||Rabbit Polyclonal antibody to GGCX (gamma-glutamyl carboxylase)|
|Background||This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||FLJ26629 antibody, VKCFD1 antibody, GGCX antibody, peptidyl-glutamate 4-carboxylase antibody, vitamin K-dependent gamma-carboxylase antibody, gamma-glutamyl carboxylase antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GGCX. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (94%), Sheep (96%), Rhesus Monkey (99%), Bovine (96%)|