GIRK1 antibody [N3C3]
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||57 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||potassium inwardly-rectifying channel, subfamily J, member 3|
|Product Description||Rabbit polyclonal antibody to GIRK1 (potassium inwardly-rectifying channel, subfamily J, member 3)|
|Background||Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq]|
|Synonyms||GIRK1 antibody, KGA antibody, KIR3.1 antibody, KCNJ3 antibody, GIRK-1 antibody, inward rectifier K(+) channel Kir3.1 antibody, G protein-activated inward rectifier potassium channel 1 antibody, inward rectifier K+ channel KIR3.1 antibody, "potassium channel, inwardly rectifying subfamily J member 3 antibody", "potassium inwardly-rectifying channel, subfamily J, member 3 antibody"|
|Cellular Localization||Membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GIRK1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Chicken, Rhesus Monkey, Bovine, Guinea pig|
|Predict Reactivity Note||Rat (98%), Chicken (91%), Rhesus Monkey (100%), Bovine (99%), Guinea pig (99%)|