|Full Name||GLI family zinc finger 3|
|Product Description||Rabbit Polyclonal antibody to GLI3 (GLI family zinc finger 3)|
|Background||This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq]|
|Synonyms||ACLS antibody, GCPS antibody, PAP-A antibody, PAPA antibody, PAPA1 antibody, PAPB antibody, PHS antibody, PPDIV antibody, GLI3 antibody, oncogene GLI3 antibody, zinc finger protein GLI3 antibody, GLI-Kruppel family member GLI3 antibody, glioma-associated oncogene family zinc finger 3 antibody, transcriptional activator GLI3 antibody, GLI family zinc finger 3 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GLI3. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Chicken, Chimpanzee|
|Predict Reactivity Note||Xenopus laevis (87%), Chicken (92%), Chimpanzee (100%)|