|Full Name||glycine receptor, beta|
|Product Description||Rabbit Polyclonal antibody to GLRB|
|Background||This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]|
|Synonyms||HKPX2 Antibody, glycine receptor, beta Antibody|
|Immunogen||KLH conjugated synthetic peptide derived from human GLRB (23-110aa)|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Bovine, Rabbit, Horse, Sheep, Pig, Chicken, Dog|