|Full Name||GDP-mannose 4,6-dehydratase|
|Product Description||Rabbit Polyclonal antibody to GMDS (GDP-mannose 4,6-dehydratase)|
|Background||GDP-mannose 4,6-dehydratase (GMD; EC 220.127.116.11) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM]|
|Synonyms||GMD antibody, SDR3E1 antibody, GMDS antibody, "short chain dehydrogenase/reductase family 3E, member 1 antibody", GDP-D-mannose dehydratase antibody, "GDP-mannose 4,6 dehydratase antibody", "GDP-mannose 4,6-dehydratase antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GMDS. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (99%), Rat (98%), Zebrafish (89%), Xenopus laevis (93%), Rhesus Monkey (99%), Bovine (97%)|