|Full Name||guanine nucleotide binding protein (G protein), q polypeptide|
|Product Description||Rabbit polyclonal antibody to GNAQ (guanine nucleotide binding protein (G protein), q polypeptide)|
|Background||Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM 600230).[supplied by OMIM]|
|Synonyms||G-ALPHA-q antibody, GAQ antibody, GNAQ antibody, guanine nucleotide-binding protein G(q) subunit alpha antibody, guanine nucleotide-binding protein alpha-q antibody, "guanine nucleotide binding protein (G protein), q polypeptide antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GNAQ. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Dog, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (93%), Xenopus laevis (96%), Dog (100%), Pig (100%), Chicken (98%), Rhesus Monkey (100%), Bovine (100%)|