|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||37 kDa (note)
|Positive Controls||293T , A431 , Jurkat , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||guanine nucleotide binding protein (G protein), beta polypeptide 1|
|Product Description||Rabbit Polyclonal antibody to GNB1 (guanine nucleotide binding protein (G protein), beta polypeptide 1)|
|Background||Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals. [provided by RefSeq]|
|Synonyms||GNB1 antibody, "beta subunit, signal-transducing proteins GS/GI antibody", "G protein, beta-1 subunit antibody", guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1 antibody, transducin beta chain 1 antibody, guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 antibody, "guanine nucleotide binding protein (G protein), beta polypeptide 1 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GNB1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Dog, Chicken, Rhesus Monkey, Bovine, Guinea pig|
|Predict Reactivity Note||Rat (100%), Xenopus laevis (96%), Dog (100%), Chicken (97%), Rhesus Monkey (100%), Bovine (100%), Guinea pig (100%)|