|Full Name||glycoprotein (transmembrane) nmb|
|Product Description||Rabbit Polyclonal antibody to GPNMB (glycoprotein (transmembrane) nmb)|
|Background||The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||HGFIN antibody, NMB antibody, GPNMB antibody, osteoactivin antibody, glycoprotein NMB antibody, transmembrane glycoprotein NMB antibody, transmembrane glycoprotein HGFIN antibody, glycoprotein nmb-like protein antibody, glycoprotein (transmembrane) nmb antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein (Potential) , Melanosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GPNMB. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (94%)|