Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||43 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||KISS1 receptor|
|Product Description||Rabbit polyclonal antibody to GPR54 (KISS1 receptor)|
|Background||The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty. [provided by RefSeq]|
|Synonyms||AXOR12 antibody, GPR54 antibody, HOT7T175 antibody, KISS1R antibody, G-protein coupled receptor OT7T175 antibody, kisspeptins receptor antibody, kiSS-1R antibody, G protein-coupled receptor 54 antibody, G-protein coupled receptor 54 antibody, hypogonadotropin-1 antibody, metastin receptor antibody, kiSS-1 receptor antibody, KISS1 receptor antibody|
|Cellular Localization||Cell membrane; Multi-pass membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human GPR54. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig|
|Predict Reactivity Note||Mouse (92%), Rat (85%), Pig (92%)|