|Full Name||G protein-coupled receptor 56|
|Product Description||Rabbit polyclonal antibody to GPR56 (G protein-coupled receptor 56)|
|Background||This gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||BFPP antibody, DKFZp781L1398 antibody, TM7LN4 antibody, TM7XN1 antibody, GPR56 antibody, 7-transmembrane protein with no EGF-like N-terminal domains-1 antibody, G-protein coupled receptor 56 antibody, G protein-coupled receptor 56 antibody|
|Cellular Localization||Cell membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GPR56. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Pig, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Human (100%), Pig (85%), Rhesus Monkey (95%), Chimpanzee (97%), Bovine (83%)|