|Full Name||GRB2-related adaptor protein|
|Product Description||Rabbit Polyclonal antibody to GRAP (GRB2-related adaptor protein)|
|Background||This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. [provided by RefSeq]|
|Synonyms||MGC64880 antibody, GRAP antibody, growth factor receptor-bound protein 2-related adaptor protein antibody, GRB2-related adapter protein antibody, GRB2-related adaptor protein antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GRAP. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (93%), Chicken (80%), Rhesus Monkey (98%), Bovine (92%)|