|Full Name||growth factor receptor-bound protein 10|
|Product Description||Rabbit Polyclonal antibody to GRB10 (growth factor receptor-bound protein 10)|
|Background||The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||GRB-IR antibody, Grb-10 antibody, IRBP antibody, KIAA0207 antibody, MEG1 antibody, RSS antibody, GRB10 antibody, insulin receptor-binding protein Grb-IR antibody, maternally expressed gene 1 antibody, GRB10 adaptor protein antibody, growth factor receptor-bound protein 10 antibody, GRB10 adapter protein antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human GRB10. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (89%), Rat (90%), Pig (97%), Chicken (94%), Rhesus Monkey (100%), Bovine (97%)|