GRB14 antibody [N1C2]
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||61 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse liver|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||growth factor receptor-bound protein 14|
|Product Description||Rabbit Polyclonal antibody to GRB14 (growth factor receptor-bound protein 14)|
|Background||The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date. [provided by RefSeq]|
|Synonyms||GRB14 antibody, GRB14 adapter protein antibody, growth factor receptor-bound protein 14 antibody|
|Cellular Localization||Cytoplasm , Golgi apparatus membrane; Peripheral membrane protein , Endosome membrane; Peripheral membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GRB14. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (86%), Bovine (97%)|