|Full Name||gremlin 2|
|Product Description||Rabbit polyclonal antibody to GREM2 (gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis))|
|Background||This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq]|
|Synonyms||CKTSF1B2 antibody, DAND3 antibody, PRDC antibody, GREM2 antibody, DAN domain family member 3 antibody, "cysteine knot superfamily 1, BMP antagonist 2 antibody", protein related to DAN and cerberus antibody, "gremlin 2, cysteine knot superfamily, homolog antibody", gremlin-2 antibody, gremlin 2 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GREM2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Rhesus Monkey (100%)|