|Full Name||adrenergic, beta, receptor kinase 1|
|Product Description||Rabbit Polyclonal antibody to GRK2 (phospho Ser670) (adrenergic, beta, receptor kinase 1)|
|Background||The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq]|
|Synonyms||BETA-ARK1 Antibody , GRK2 Antibody , ADRBK1 Antibody , adrenergic, beta, receptor kinase 1 Antibody , BARK1 Antibody|
|Target||GRK2 (phospho Ser670)|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GRK2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Pig (100%), Bovine (100%)|