|Full Name||cytohesin 3|
|Product Description||Rabbit Polyclonal antibody to GRP1 (cytohesin 3)|
|Background||This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq]|
|Synonyms||ARNO3 antibody, GRP1 antibody, PSCD3 antibody, CYTH3 antibody, general receptor of phosphoinositides 1 antibody, "pleckstrin homology, Sec7 and coiled-coil domains 3 antibody", ARF nucleotide-binding site opener 3 antibody, cytohesin-3 antibody, "PH, SEC7 and coiled-coil domain-containing protein 3 antibody", cytohesin 3 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GRP1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chimpanzee|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Chimpanzee (100%)|