GSK3 beta antibody [C1C3]
|Applications||ICC/IF, IHC-P, WB|
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
Western blot : The use of GTX111192 for rat is based on IHC-P testing.Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||47 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||glycogen synthase kinase 3 beta|
|Product Description||Rabbit Polyclonal antibody to GSK3 beta (glycogen synthase kinase 3 beta)|
|Background||Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase (see GYS1, MIM 138570). Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM]|
|Synonyms||GSK3B antibody, GSK-3 beta antibody, serine/threonine-protein kinase GSK3B antibody, glycogen synthase kinase-3 beta antibody, GSK3beta isoform antibody, glycogen synthase kinase 3 beta antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GSK3 beta. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Pig, Sheep, Bovine|
|Predict Reactivity Note||Zebrafish (83%), Pig (90%), Sheep (90%), Bovine (98%)|