|Full Name||glutathione S-transferase alpha 4|
|Product Description||Rabbit Polyclonal antibody to GSTA4 (glutathione S-transferase alpha 4)|
|Background||Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. [provided by RefSeq]|
|Synonyms||DKFZp686D21185 antibody, GSTA4-4 antibody, GTA4 antibody, GSTA4 antibody, glutathione transferase A4-4 antibody, glutathione S-alkyltransferase A4 antibody, glutathione S-transferase A4-4 antibody, GST class-alpha member 4 antibody, glutathione S-aralkyltransferase A4 antibody, S-(hydroxyalkyl)glutathione lyase A4 antibody, glutathione S-aryltransferase A4 antibody, glutathione S-transferase A4 antibody, glutathione S-transferase alpha 4 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GSTA4. The exact sequence is proprietary.|
|Species Reactivity||Human, Pig|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Dog (91%), Rhesus Monkey (97%), Bovine (93%)|