|Full Name||galactosidase, alpha|
|Product Description||Rabbit Polyclonal antibody to Galactosidase alpha (galactosidase, alpha)|
|Background||This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq]|
|Synonyms||GALA antibody, GLA antibody, agalsidase alfa antibody, alpha-gal A antibody, melibiase antibody, alpha-D-galactoside galactohydrolase 1 antibody, alpha-galactosidase A antibody, alpha-D-galactosidase A antibody, "galactosidase, alpha antibody"|
|Cellular Localization||Lysosome |
|Specificity||Knockdown/Knockout validation was supported by customer review data.|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Galactosidase alpha. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (82%), Bovine (80%)|