|Product Description||Rabbit polyclonal antibody to Galactosylceramidase (galactosylceramidase)|
|Background||This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Synonyms||GALC antibody, galactosylceraminidase antibody, galactocerebrosidase antibody, galactocerebroside beta-galactosidase antibody, galactosylceramide beta-galactosidase antibody, GALCERase antibody, galactosylceramidase antibody|
|Cellular Localization||Lysosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Galactosylceramidase. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Dog (87%), Pig (87%), Rhesus Monkey (95%), Bovine (84%)|