|Full Name||sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)|
|Product Description||Rabbit Polyclonal antibody to Gamma Sarcoglycan (sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein))|
|Background||This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq]|
|Synonyms||SGCG Antibody , DAGA4 Antibody , sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) Antibody , SCG3 Antibody , TYPE Antibody , DMDA1 Antibody , A4 Antibody , DMDA Antibody , SCARMD2 Antibody , LGMD2C Antibody , MAM Antibody|
|Cellular Localization||Cell membrane , sarcolemma; Single-pass type II membrane protein (By similarity) , Cytoplasm , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Gamma Sarcoglycan. The exact sequence is proprietary.|
|Species Reactivity||Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Dog, Rabbit, Bovine|
|Predict Reactivity Note||Human (100%), Dog (94%), Rabbit (88%), Bovine (83%)|