|Product Description||Rabbit polyclonal antibody to Gelsolin (gelsolin (amyloidosis, Finnish type))|
|Background||The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||DKFZp313L0718 antibody, GSN antibody, brevin antibody, actin-depolymerizing factor antibody, gelsolin antibody|
|Cellular Localization||Isoform 2: Cytoplasm , cytoskeleton , Isoform 1: Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Gelsolin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Sheep, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (95%), Chicken (81%), Sheep (96%), Bovine (96%)|