Gelsolin antibody [C2C3], C-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||86 kDa (note)
|Positive Controls||H1299 , HeLa , human plasma , rat plasma , mouse plasma|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Product Description||Rabbit Polyclonal antibody to Gelsolin (gelsolin)|
|Background||The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||DKFZp313L0718 antibody, GSN antibody, brevin antibody, actin-depolymerizing factor antibody, gelsolin antibody|
|Cellular Localization||Isoform 2: Cytoplasm , cytoskeleton , Isoform 1: Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Gelsolin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Chicken, Sheep, Bovine|
|Predict Reactivity Note||Chicken (81%), Sheep (98%), Bovine (98%)|