|Product Description||Mouse Monoclonal antibody [GT667] to Gelsolin (gelsolin)|
|Background||The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||ADF antibody , AGEL antibody , GSN antibody , Gelsolin antibody [GT667] antibody , Gelsolin antibody|
|Cellular Localization||Isoform 2: Cytoplasm , cytoskeleton , Isoform 1: Secreted|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Gelsolin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Sheep, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (90%), Chicken (80%), Sheep (96%), Bovine (95%)|