|Full Name||glutamate receptor, ionotropic, kainate 3|
|Product Description||Rabbit polyclonal antibody to GluR 7 (glutamate receptor, ionotropic, kainate 3)|
|Background||Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq]|
|Synonyms||EAA5 antibody, GLR7 antibody, GLUR7 antibody, GluR7a antibody, GRIK3 antibody, "dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)) antibody", glutamate receptor 7 antibody, gluR-7 antibody, excitatory amino acid receptor 5 antibody, "glutamate receptor, ionotropic kainate 3 antibody", "glutamate receptor, ionotropic, kainate 3 antibody"|
|Cellular Localization||Cell membrane; Multi-pass membrane protein , Cell junction , synapse , postsynaptic cell membrane; Multi-pass membrane protein |
|Target||GluR 7 |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GluR 7. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (93%), Bovine (93%)|