|Full Name||nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)|
|Product Description||Rabbit Polyclonal antibody to Glucocorticoid receptor (nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor))|
|Background||The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. [provided by RefSeq]|
|Synonyms||GCCR antibody, GCR antibody, GR antibody, GRL antibody, NR3C1 antibody, nuclear receptor subfamily 3 group C member 1 variant NS-1 antibody, nuclear receptor subfamily 3 group C member 1 variant DL-1 antibody, glucocorticoid receptor antibody, glucocorticoid nuclear receptor variant 1 antibody, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Glucocorticoid receptor. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Cat, Pig, Sheep, Bovine, Guinea pig|
|Predict Reactivity Note||Dog (84%), Cat (91%), Pig (84%), Sheep (86%), Bovine (87%), Guinea pig (83%)|