Glucosidase I antibody [N1N3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||92 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||mannosyl-oligosaccharide glucosidase|
|Product Description||Rabbit polyclonal antibody to Glucosidase I (mannosyl-oligosaccharide glucosidase )|
|Background||This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||CDG2B antibody, GCS1 antibody, MOGS antibody, mannosyl-oligosaccharide glucosidase antibody, glucosidase I antibody, processing A-glucosidase I antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Single-pass type II membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Glucosidase I. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (87%)|