|Product Description||Rabbit Polyclonal antibody to Glutaminase C (glutaminase isoform 3)|
|Background||Sahai (1983) [PubMed 6825316] demonstrated phosphate-activated glutaminase (EC 22.214.171.124) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.[supplied by OMIM]|
|Synonyms||GLS1 Antibody , GLS Antibody , GAM Antibody , glutaminase Antibody , AAD20 Antibody , GAC Antibody|
|Cellular Localization||Mitochondrion |
|Specificity||Specific for GAC but not KGA isoform|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Glutaminase C. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (100%)|