|Full Name||glutathione reductase|
|Product Description||Rabbit Polyclonal antibody to Glutathione Reductase|
|Background||This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq]|
|Synonyms||MGC78522 antibody, GSR antibody, GRase antibody, GR antibody, glutathione reductase, mitochondrial antibody, glutathione reductase antibody|
|Cellular Localization||Mitochondrion , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Glutathione Reductase. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (84%)|