|Full Name||glypican 3|
|Product Description||Mouse Monoclonal antibody [GT764] to GPC3 (glypican 3)|
|Background||Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome. [provided by RefSeq]|
|Synonyms||DGSX antibody , GPC3 antibody [GT764] antibody , GPC3 antibody , GTR22 antibody , MXR7 antibody , OCI5 antibody , SDYS antibody , SGB antibody , SGBS antibody , SGBS1 antibody , glypican 3 antibody|
|Cellular Localization||Cell membrane; Lipid-anchor , GPI-anchor; Extracellular side , Secreted glypican-3: Secreted , extracellular space|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human GPC3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (96%), Bovine (81%)|