Full Name | glypican 3 |
Background | Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome. [provided by RefSeq] |
Synonyms | DGSX antibody , GPC3 antibody , GPC3 antibody , GTR22 antibody , MXR7 antibody , OCI5 antibody , SDYS antibody , SGB antibody , SGBS antibody , SGBS1 antibody , glypican 3 antibody |
Cellular Localization | Cell membrane; Lipid-anchor , GPI-anchor; Extracellular side , Secreted glypican-3: Secreted , extracellular space |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human GPC3. The exact sequence is proprietary. |
Antigen Species | Human |
Species Reactivity | Human |
Predicted Cross Reactivity species Predicted cross-reactivity: Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive. Please note that we are only able to guarantee products to work in applications and species in which they have been tested. | Mouse, Rat, Chimpanzee, Bovine |
Predict Reactivity Note | Mouse (81%), Rat (80%), Chimpanzee (96%), Bovine (85%) |
Conjugation | Unconjugated |