|Full Name||grancalcin, EF-hand calcium binding protein|
|Product Description||Rabbit Polyclonal antibody to Grancalcin (grancalcin, EF-hand calcium binding protein)|
|Background||This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. [provided by RefSeq]|
|Synonyms||GCL antibody, GCA antibody, grancalcin antibody, "grancalcin, penta-EF-hand protein antibody", "grancalcin, EF-hand calcium-binding protein antibody", "grancalcin, EF-hand calcium binding protein antibody"|
|Cellular Localization||Cytoplasm , Membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Grancalcin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Rhesus Monkey|
|Predict Reactivity Note||Mouse (88%), Rat (87%), Xenopus laevis (81%), Rhesus Monkey (93%)|