|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||34 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , mouse liver , rat heart , rat liver|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||hydroxyacyl-CoA dehydrogenase|
|Product Description||Rabbit Polyclonal antibody to HADH (hydroxyacyl-CoA dehydrogenase)|
|Background||This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene. [provided by RefSeq]|
|Synonyms||HAD antibody, HADH1 antibody, HADHSC antibody, HCDH antibody, HHF4 antibody, MGC8392 antibody, MSCHAD antibody, SCHAD antibody, HADH antibody, L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain antibody, hydroxyacyl-coenzyme A dehydrogenase, mitochondrial antibody, short-chain 3-hydroxyacyl-CoA dehydrogenase antibody, medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase antibody, hydroxyacyl-CoA dehydrogenase antibody|
|Cellular Localization||Mitochondrion matrix|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HADH. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Pig (92%), Chicken (81%), Rhesus Monkey (96%), Bovine (90%)|