|Full Name||HMG-box transcription factor 1|
|Product Description||Rabbit Polyclonal antibody to HBP1 (HMG-box transcription factor 1)|
|Background||Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.|
|Synonyms||FLJ16340 antibody, HBP1 antibody, HMG box transcription factor 1 antibody, HMG box-containing protein 1 antibody, high mobility group box transcription factor 1 antibody, HMG-box transcription factor 1 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HBP1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (95%), Rat (94%), Xenopus laevis (81%), Pig (97%), Chicken (87%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (97%)|