|Full Name||histone deacetylase 1|
|Product Description||Rabbit Polyclonal antibody to HDAC1 (histone deacetylase 1)|
|Background||Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq]|
|Synonyms||DKFZp686H12203 antibody, GON-10 antibody, HD1 antibody, RPD3 antibody, RPD3L1 antibody, HDAC1 antibody, histone deacetylase 1 antibody, "reduced potassium dependency, yeast homolog-like 1 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HDAC1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Drosophila, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Zebrafish (97%), Drosophila (86%), Xenopus laevis (97%), Chicken (98%), Bovine (100%)|