|Full Name||histone deacetylase 3|
|Product Description||Rabbit polyclonal antibody to HDAC3 (histone deacetylase 3)|
|Background||Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq]|
|Synonyms||HD3 antibody, RPD3 antibody, RPD3-2 antibody, HDAC3 antibody, SMAP45 antibody, histone deacetylase 3 antibody|
|Target||Histone Deacetylase 3|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HDAC3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Zebrafish (94%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%)|