|Full Name||histone deacetylase 8|
|Product Description||Rabbit Polyclonal antibody to HDAC8 (histone deacetylase 8)|
|Background||Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. [provided by RefSeq]|
|Synonyms||HD8 antibody, HDACL1 antibody, RPD3 antibody, HDAC8 antibody, histone deacetylase 8 antibody, histone deacetylase-like 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HDAC8. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Bovine|
|Predict Reactivity Note||Xenopus laevis (88%), Bovine (96%)|