HGS antibody [C2C3], C-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||86 kDa (note)
|Positive Controls||H1299 , HeLa , mouse brain , rat brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||hepatocyte growth factor-regulated tyrosine kinase substrate|
|Product Description||Rabbit Polyclonal antibody to HGS (hepatocyte growth factor-regulated tyrosine kinase substrate)|
|Background||The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq]|
|Synonyms||FLJ11421 antibody, FLJ39878 antibody, HRS antibody, HGS antibody, protein pp110 antibody, human growth factor-regulated tyrosine kinase substrate antibody, hepatocyte growth factor-regulated tyrosine kinase substrate antibody|
|Cellular Localization||Cytoplasm , Early endosome membrane; Peripheral membrane protein; Cytoplasmic side , Endosome , multivesicular body membrane; Peripheral membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human HGS. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Dog (93%), Rhesus Monkey (98%), Bovine (90%)|