|Full Name||hypoxia inducible factor 1, alpha subunit inhibitor|
|Product Description||Rabbit Polyclonal antibody to HIF1AN (hypoxia inducible factor 1, alpha subunit inhibitor)|
|Background||Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. |
|Synonyms||DKFZp762F1811 antibody, FIH1 antibody, FLJ20615 antibody, FLJ22027 antibody, HIF1AN antibody, FIH-1 antibody, factor inhibiting HIF1 antibody, peptide-aspartate beta-dioxygenase antibody, factor inhibiting HIF-1 antibody, hypoxia-inducible factor 1-alpha inhibitor antibody, hypoxia-inducible factor asparagine hydroxylase antibody, hypoxia inducible factor 1, alpha subunit inhibitor antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HIF1AN. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Zebrafish (86%), Xenopus laevis (90%), Bovine (99%)|