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1 .GTX30646 HIF1AN antibody

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HIF1AN antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsEM, ICC/IF, IHC, IHC-P, IP, WB
  • Species reactivityHuman, Mouse, Rat
Cat No: GTX30646
Package Price Qty
100 μlUSD 339.00
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  • Anti-HIF1AN antibody used in Immunohistochemistry (IHC). GTX30646
  • Anti-HIF1AN antibody used in Western Blot (WB). GTX30646
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  • Datasheet
  • Application Information: HIF1AN antibody

Catalog Number GTX30646
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Product Name HIF1AN antibody
See all HIF1AN products
ApplicationsEM, ICC/IF, IHC, IHC-P, IP, WB
Application NoteWestern Blot 1:1000-1:5000
Electron Microscopy
Immunocytochemistry/Immunofluorescence
Immunohistochemistry 1:100
Immunohistochemistry-Paraffin
Immunoprecipitation 1:10-1:500

This Factor Inhibiting HIF-1 antibody is useful for Immunohistochemistry, Immunoprecipitation and Western Blot. In WB, a band at ~40.3 kDa is seen. Use in Immunocytochemistry/immunofluorescence, Immunohistochemistry-Paraffin and Electron Microscopy reported in scientific literature (PMID 17003483)
Positive ControlsRat astrocytes and C6 and U251 gliomas
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)

  • Specifications: HIF1AN antibody

Full Namehypoxia inducible factor 1, alpha subunit inhibitor
BackgroundFactor Inhibiting HIF1 (FIH1 or HIF1AN) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.
SynonymsDKFZp762F1811, FIH1, FLJ20615, FLJ22027
SpecificityThis antibody is specific for HIF1AN protein.
HostRabbit
ClonalityPolyclonal
ImmunogenA C-terminal region synthetic peptide made to the human HIF1AN protein sequence (between residues 300 and the C-terminus).
Antigen SpeciesHuman
Species ReactivityHuman, Mouse, Rat
ConjugationUnconjugated

  • Storage Conditions: HIF1AN antibody

Storage Buffer0.1 ml of purified antibody [1 mg/ml]in Tris-citrate/phosphate [pH 7-8] buffer containing 0.1% Sodium Azide.
Storage InstructionStore at 4 degrees Celcius.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Lung > Other
  • Cancer > Type of cancer > Prostate cancer
  • Disease Related > Alzheimer's disease
  • Neuroscience > Disorder > Alzheimer's disease
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HIF1AN antibody validated data
  • Anti-HIF1AN antibody used in Immunohistochemistry (IHC). GTX30646
    • GTX30646 IHC Image
      Immunohistochemistry: Factor Inhibiting HIF-1 Antibody [GTX30646] - Detection of FIH-1 in rat brain tissue.
      Top
  • Anti-HIF1AN antibody used in Western Blot (WB). GTX30646
    • GTX30646 WB Image
      Western Blot: Factor Inhibiting HIF-1 Antibody [GTX30646] - Detection of FIH-1 in rat and human samples
      Top
  • Anti-HIF1AN antibody used in Immunohistochemistry (IHC). GTX30646
    • GTX30646 IHC Image
      Immunohistochemistry: Factor Inhibiting HIF-1 Antibody [GTX30646] - Detection of FIH-1 in rat brain tissue.
      Top
  • Anti-HIF1AN antibody used in Western Blot (WB). GTX30646
    • GTX30646 WB Image
      Western Blot: Factor Inhibiting HIF-1 Antibody [GTX30646] - Detection of FIH-1 in rat and human samples
      Top
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All products are for research use only—Not for use in diagnostic procedures.