|Full Name||ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)|
|Product Description||Rabbit Polyclonal antibody to HIP2 (ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast))|
|Background||The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]|
|Synonyms||DKFZp564C1216 antibody, DKFZp686J24237 antibody, E2-25K antibody, HIP2 antibody, HYPG antibody, LIG antibody, UBE2K antibody, HIP-2 antibody, ubiquitin-conjugating enzyme E2(25K) antibody, E2(25K) antibody, "ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) antibody", ubiquitin-conjugating enzyme E2-25K antibody, ubiquitin-conjugating enzyme E2-25 KDA antibody, ubiquitin-protein ligase antibody, ubiquitin carrier protein antibody, huntingtin interacting protein 2 antibody, ubiquitin-conjugating enzyme E2 K antibody, huntingtin-interacting protein 2 antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HIP2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (100%), Xenopus laevis (98%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|