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1 .GTX102763 HLA-DPB1 antibody

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HLA-DPB1 antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsWB
  • Species reactivityHuman
Cat No: GTX102763
Package Price Qty
25 μlUSD 119.00
100 μlUSD 319.00
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  • Anti-HLA-DPB1 antibody used in Western Blot (WB). GTX102763
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  • Datasheet
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  • Application Information: HLA-DPB1 antibody

Catalog Number GTX102763
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Product Name HLA-DPB1 antibody
See all HLA-DPB1 products
ApplicationsWB
Application Note
Suggested dilutionReference
Western Blot (WB)1:500-1:3000*  
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Target Size29 kDa (note)
Positive ControlsRaji
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified by antigen-affinity chromatography.

  • Specifications: HLA-DPB1 antibody

Full Namemajor histocompatibility complex, class II, DP beta 1
BackgroundHLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq]
SynonymsDPB1 antibody, HLA-DP1B antibody, HLA-DPB antibody, HLA-DPB1 antibody, MHC class II HLA-DRB1 antibody, MHC HLA DPB1 antibody, "HLA class II histocompatibility antigen, DP(W4) beta chain antibody", "HLA class II histocompatibility antigen, DP beta 1 chain antibody", major histocompatibility complex class II HLA DPB1 protein antibody, MHC class II HLA-DP-beta antibody, MHC class II HLA-DP-beta-1 antibody, beta1 domain MHC class II HLA DPB antibody, MHC class II antigen DPB1 antibody, MHC class II antigen DP beta 1 chain antibody, MHC class II antigen DPbeta1 antibody, MHC class II antigen beta chain antibody, HLA DP14-beta chain antibody, "HLA-DP histocompatibility type, beta-1 subunit antibody", "major histocompatibility complex, class II, DP beta 1 antibody"
Cellular LocalizationMembrane; Single-pass type I membrane protein
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenRecombinant protein encompassing a sequence within the center region of human HLA-DPB1. The exact sequence is proprietary.
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: HLA-DPB1 antibody

Storage Buffer1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Breast > Other
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  • Cancer > Type of cancer > Leukemia > Lymphoma > B cell
  • Cancer > Type of cancer > Leukemia > Myeloid > AML
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HLA-DPB1 antibody validated data
  • Anti-HLA-DPB1 antibody used in Western Blot (WB). GTX102763
    • GTX102763 WB Image
      Sample (30 ug of whole cell lysate)

      A: Raji

      12% SDS PAGE

      GTX102763 diluted at 1:500
      Top
  • Anti-HLA-DPB1 antibody used in Western Blot (WB). GTX102763
    • GTX102763 WB Image
      Sample (30 ug of whole cell lysate)

      A: Raji

      12% SDS PAGE

      GTX102763 diluted at 1:500
      Top
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Target Bioinfo/ Predicted Isoform Cross Reactivity
SpeciesGene nameGene IDSwissProtOMIMIsoform (mRNA)Protein Accession#MW
Homo sapiensHLA-DPB13115P04440, Q5EP52142858NM_002121NP_00211229.17
    *MSDS
    MSDS-Glycerol.pdf
    MSDS-PBS.pdf
    MSDS-Thimerosal.pdf
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All products are for research use only—Not for use in diagnostic procedures.