|Full Name||high mobility group AT-hook 1|
|Product Description||Rabbit polyclonal antibody to HMGA1 (high mobility group AT-hook 1)|
|Background||This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||HMG-R antibody, HMGA1A antibody, HMGIY antibody, MGC12816 antibody, MGC4242 antibody, MGC4854 antibody, HMGA1 antibody, high mobility group protein HMG-I/HMG-Y antibody, high-mobility group (nonhistone chromosomal) protein isoforms I and Y antibody, high mobility group protein R antibody, HMG-I(Y) antibody, nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y antibody, high mobility group protein A1 antibody, high mobility group AT-hook 1 antibody|
|Cellular Localization||Nucleus |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HMGA1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Dog (100%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (100%)|